Abstract

Medicinal plants have been used for centuries to treat trauma, infection, sickness, and injury as these are affordable, easy to access and have fewer side effects than commercial pharmaceuticals. Recent research has shown that several medicinal plants can treat wounds using in vivo and in vitro pre-clinical models of wound recovery. Furthermore, the mechanisms by which these medicinal plants enhance wound therapy have also been revealed. Medicinal herbs have been shown in research to have the ability to have an antioxidant effect, to promote angiogenesis, to activate NF-B, to favor specific pro-inflammatory cytokines, to boost the appearance of iNOS and α-1 type-1 collagen, and to favor certain pro-inflammatory cytokines. All these effects can be brought about by medicinal herbs. Considering this, throughout this evaluation, an effort was made to provide a glimpse into freshly discovered medicinal plants that have wound recovery mechanisms and may be effective in the treatment and the invention of new wound-healing pharmaceuticals. Herbal medicines involve disinfection, debridement, and creating a healing environment. The purpose of the study was to review and gather the evidence related to the use of medicinal plants in wound healing. The use of herbal remedies is found to be both affordable and effective, mainly when used in conjunction with wound healing, bacterial activity and reducing oxidative stress in animals. During this evaluation, the cellular processes of recently discovered medicinal plants with a capacity for wound healing were brought to light. These mechanisms can potentially be helpful in therapeutic practice and the advancement of innovative medications for treating wounds. Several factors can delay the wound-healing process such as anemia, diabetes, nutritional deficiency, hematoma, local infections, etc. In the treatment of wounds, many medicinal plants and other herbal immunomodulators are considered useful. Through different pathways, these herbal ointments promote healing and regeneration of the lost tissues without producing side effects.