Abstract

Objectives: To determine morphological spectrum of gall bladder diseases at a tertiary care centre of Karachi and to correlate with age and gender
Methodology: Data was collected from histopathological records between June 2017 to June 2019. Relevant data including registration number, age, gender of the patients and diagnosis were recorded. Data was entered and analyzed using SPSS version 21. P-value < 0.05 was considered as significant.
Results: In our study, patients 26-35 years of age were predominantly found to be susceptible to gall bladder diseases and male to female ratio was 1:3.7. Out of the total 150 cases, 75 were identified as chronic cholecystitis with cholelithiasis whereas 32 cases of chronic cholecystitis were without stones or any other associated pathology. Out of 150 cases, 40 were seen in combination with different pathologies. Our series also included three cases of adenocarcinoma and all of these were diagnosed in females. Significant association of diagnosis was seen with gender and type of stones (p-value = 0.03) (p-value = 0.01) respectively.
Conclusion: In our study, chronic cholecystitis with cholelithiasis was the most common finding which was most predominantly seen in females. Younger age group was mainly affected in both genders. Mixed type of gall stones were the most common stones found in our series.