Abstract

This study was suggested to show apoptotic markers level in Hepatitis C Carcinoma (HCC) patients related to Hepatitis C Virus (HCV) infection and evaluate the Fas and Fas-L levels in each of non-cancerous individuals (controls), HCC and non-HCC patients to show the apoptosis levels which reflects the progression of inflammation and fibrosis in HCV patients. The collected samples were tested by kinetic, ELISA, RT-PCR and other molecular techniques. The obtained results showed that the Fas-upregulations don’t change in case of positive viral C infection related to HCC and also in non-HCC. But in negative HCV-RNA, Fas-expression in HCC patients is significant. So, the conclusion is neither Fas nor Fas-L may be affected by viral C infection.