Article Information

Title: PREVALENCE OF INSULIN RESISTANCE IN TYPE-2 DIABETIC PATIENTS

Authors: Nazir Shah, Aman Ullah, Salma Attaullah

Journal: Journal of Postgraduate Medical Institute

HEC Recognition History
Category From To
Y 2023-07-01 2024-09-30
Y 2022-07-01 2023-06-30
Y 2021-07-01 2022-06-30
Y 2020-07-01 2021-06-30

Publisher: Postgraduate Medical Institute

Country: Pakistan

Year: 2008

Volume: 22

Issue: 1

Language: English

Keywords: HypertensionInsulin ResistanceMetabolic syndromeType-II diabetes mellitus

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Abstract

Objective: To determine the prevalence of insulin resistance in patients of type-2 diabetes mellitus inpopulation of NWFP, using the National Cholesterol Education Program Adult Treatment Panel-IIIdefinition of insulin resistance,(modified for Asians)Material and Methods: This analytical study was performed in Fauji Foundation Hospital andHayatabad Medical Complex Peshawar. Two hundred and eighty patients of type-2 diabetes mellitus of age30 or above were included from the hospital OPD and wards. Those patients, who were having high waistcircumference because of reasons other than abdominal fat like pregnancy, ascites, abdominal tumors etc,were excluded from the study. Patients with severe infection and inflammatory conditions were alsoexcluded. All the patients were examined for waist circumference and blood pressure, and investigated forfasting blood sugar, triglyceride and S HDL. The above mentioned criteria was applied to know whether apatients is insulin resistant or not.Results: Two hundred & eighty patients of Type-2 diabetes mellitus were collected randomly from thehospital OPD. Ninety-five were males and 185 were females. Seventy eight percent 78% (n=219) of thepatients were fulfilling the criteria for metabolic syndrome (insulin resistance). The prevalence ofmetabolic syndrome was almost equal in male 77% (n=73) and females 79% (n=146). The ratio of centralobesity was more in the females 78% (n=144) than in the males 70% (n=67). The total prevalence ofhypertension was 71% (n=199). The ratio of hypertension was more in the male 75% (n=71) than in thefemale 67% (n=124).Conclusion: Insulin resistance is very common in type-2 diabetes mellitus. Treating the insulin resistancewith insulin sensitizing drugs will prove beneficial regarding the diabetic control and prevention of itsmacro vascular complications.

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